We study nonlocal first-order equations arising in the theory of dislocations. We prove the existence and uniqueness of the solutions of these equations in the case of positive and negative velocities, under suitable regularity assumptions on the initial data and the velocity. These results are based on new L¹-type estimates on the viscosity solutions of first-order Hamilton-Jacobi Equations appearing in the so-called ``level-sets approach''. Our work is inspired by and simplifies a recent work of Alvarez, Cardaliaguet and Monneau.